Health Hazard Of Xylene

Xylene can enter the environment when it is made packaged shipped or used.

Health hazard of xylene. A literature review sharada t. Reena kandyala department of oral pathology vishnu dental college bhimavaram 534 202 andhra pradesh india. Malathi 2 1 senior lecturer department of oral pathology faculty of dental sciences sri ramachandra university chennai india.

Presently health hazards of xylene are well documented and a safer substitute is an absolute. Exposure to this chemical and loud noise may cause greater hearing loss than expected from noise exposure alone. In routine histopathology xylene has been used in tissue processing and staining.

The most common side effect of inhaled xylene is depression of the central nervous system causing dizziness headache nausea and vomiting. Oral ld 50 for rats is 4300 mg kg. 4 5 xylene causes health effects from both acute 14 days and also chronic 365 days exposure.

As every other profession became cauti xylene is an aromatic hydrocarbon known for its wide usage in tissue processing staining and cover slipping in the histology laboratory. An overview of its health hazards and preventive measures. Can cause dry red cracked skin dermatitis following skin contact.

Most xylene that is accidentally released evaporates into the air although some is released into rivers or lakes. Xylene is a liquid and it can leak into soil surface water creeks streams rivers or groundwater. The hazards of xylene are well documented making it a potential occupational hazard for the histopathological technicians.

Xylene is flammable but of modest acute toxicity with ld 50 ranges from 200 to 5000 mg kg for animals. Conclusions cannot be drawn from the limited studies available. In extreme concentrations of xylene approximately 10 000 ppm problems with coordination loss of consciousness respiratory failure and even death may occur.